The Servant, the Messiah describes His calling in Isaiah 49:1: Listen, O isles, unto me; and hearken, ye peoples, from far: Jehovah has called me from the womb; from the bowels of my mother has he made mention of my name:
The verse begins with a call for the whole world to listen to what the Servant has to say. He then points out that He, the Servant, the Messiah, was elected by God for this specific mission: Jehovah has called me from the womb; from the bowels of my mother. It is interesting to note that, while there are many messianic prophecies that mention the mother of the Messiah, as it does here, the father is never mentioned.
This is no accident, for according to Isaiah 7:14, the Messiah was to be born of a virgin. Whenever the father of the Messiah is described or mentioned, it is God Himself who turns out to be that Father. In all messianic prophecy, there is never the mention of a human father, only a mother. In this case, the mother is Mary or, more correctly, Miriam.
What was prophesied in Isaiah 7:14 was fulfilled in Matthew 1:21 and Luke 1:31. The point of verse 1 is that the Messiah was appointed to His task when He was still in the womb of His mother. This was indeed true of Yeshua (Lk. 1:30-33).
Gabriel informed Mary that she would conceive by the overshadowing power of the Holy Spirit. That which was conceived was holy, the Son of God. This is the One to whom God the Father will give the throne of his father David. In Matthew 1:21, this is the One who will save His people from their sins. Indeed, while the Messiah was still in the womb of His mother, God already had a specific commission for Him.